Progress of Cryogenics and Isotopes Separation , ISSN: 1582-2575
2004, Volume 7, Issue 13+14

Deuterium-Depleted Water, Short History and New

Ioan Stefanescu * , Radu Tamaian , Gheorghe Titescu

National R&D Institute of Cryogenics and Isotopic Separations

*Corresponding author: Ioan Stefanescu, e-mail:

Published: October 2004


Deuterium-depleted water represent water that has an isotopic content smaller than 144 ppm D/(D+H) that is the natural isotopic content of water. DDW is a non-toxic product. Knowing that deuterium content of water has a big influence on living organisms, beginning with 1996 NIR-DCIT I.C.S.I. Rm. Valcea cooperated with Romanian specialized institutes for biological effect's evaluation of DDW. The investigations lead to the conclusion that DDW caused a tendency towards the increase of the basal tone, accompanied by the intensification of the vasoconstrictor effects. Animals treated with DDW showed an increase of the resistance both to sub lethal and to lethal gamma radiation doses. DDW stimulates immune defense reactions. Investigations regarding artificial reproduction of fish with DDW fecundated solutions confirmed favorable influence in embryo growth stage and resistance in next growth stages. One can remark the favorable influence of DDW on biological process at plants in various ontogenetic stages.


Deuterium depletion, biological effects.

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